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KMID : 0438420080150010085
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Korean Journal of Bone Metabolism
2008 Volume.15 No. 1 p.85 ~ p.89
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A Case of Parathyroid Carcinoma Mimicking Bone Tumor
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Kim Eun-A
Lee Jung-Jin
Ha Ki-Cheol
Chung Young-Kuk
Yoo Sung-Soo
Kim So-Hun
Hong Seong-Bin
Nam Moon-Suk
Kim Yong-Seong
Kim Sei-Joong
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Abstract
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Background: Most of primary hyperparathyroidism result from parathyroid adenoma, parathyroid carcinoma is rare, comprising only 0.1% to 5% of all patients with primary hyperparathyroidism. It present with severe hypercalcemia, bone disease, palpable neck mass, and renal involvement.
Case: A 37-year-old woman was admitted to the hospital due to pain on the left elbow. MRI of elbow showed multi-septated mass with heterogenous T2 signal intensity. The excisional biopsy of ulnar showed increased number of osteoclast. Then, she was transferred to endocrinology department. Elevated serum calcium and parathyroid hormone (PTH) concentration allowed the diagnosis of hyperparathyroidism. Postoperative histological diagnosis was parathyroid carcinoma with focal invasion to thyroid parenchyma. After operation, the patients was treated with vitamin D and calcium because of hungry bone syndrome. The intact PTH level decreased and calcium level return to normal range.
Conclusion: We reported a rare case of a parathyroid carcinoma mimics bone tumor with mild increased serum calcium level.
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KEYWORD
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Parathyroid, Carcinoma
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